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Simulation of caspases apoptotic signalling pathway in a tuple space-based bioinformatics infrastructure

Maura Cárdenas-García, Pedro Pablo González-Pérez, Sara Montagna
Motivation and Objectives Understanding intracellular communication processes is essential, since they allow the cell to perform the totality of its functions. Among them each cell has a self-destruction system that starts and operates in a regulated manner. It is called apoptosis, and includes the decision to start self-destruction as well as the proper execution of the apoptotic program. Caspases, a family of cysteine proteases, are the central regulators of apoptosis. As such, it requires the coordinated activation and execution of multiple sub programmes.
EMBnet.journal 18(B), 2012
@article{nettab-embnetjournal2012,
	journal = {EMBnet.journal},
	author = {Cárdenas-García, Maura and González-Pérez, Pedro Pablo and Montagna, Sara },
	title = {Simulation of caspases apoptotic signalling pathway in a tuple space-based bioinformatics infrastructure},
	year = 2012,
	status = {Published},
	number = {B},
	venue = {--},
	url = {http://journal.embnet.org/index.php/embnetjournal/article/view/563},
	volume = 18}